Below are our current protease-related job listings:

POST-DOCTORAL FELLOWSHIP -Dept. Medical Sciences, Università “A. Avogadro”, Novara, Italy
Nano-bio-imaging of the autophagy-lysosomal pathway in cancer
PostDoc position available in the Laboratory of CIRO ISIDORO for the period 2009-2010 (renewable for 1 year) to work on NanobioImaging of autophagy and lysosomal proteolysis (nanoparticles functionalized with fluorogenic tracers of vesicular traffic and of cathepsin-mediated proteolysis). Application deadline is 11th November 2009. Selection on 18th November 2009. Call and application form can be found at the following link: Click Here

Work starts in December 2009. Salary: 22.000 euro/year plus approx 12.000 euro (gross)/year for subsistence costs and travel reimbursement. Ideal candidates: 1. should have a solid background in cell biology, biochemistry and molecular biology; 2. should be enthusiastic to work in group in a stimulating and exciting environment. Please, contact immediately via e-mail.

CONTACT: CIRO ISIDORO, Professor of Pathology, Dept. Medical Sciences, Università “A. Avogadro”, Novara, Italy. E-mail: isidoro@med.unipmn.it.

Two PhD positions in the field of Protease Proteomics: Substrate Profiling of Cysteine Proteases in Physiology and Pathology. Institute for Molecular Medicine & Cell Research, University of Freiburg, GermanyFunded by the Emmy-Noether Programme of the Deutsche Forschungsgemeinschaft, the laboratory currently has two open positions for motivated PhD students to work in the area of “protease proteomics”. These projects employ a diverse array of complementary techniques, including molecular biology, cell culture, protein chemistry, quantitative proteomics and bioinformatics.

Please send your application by mail or e-mail to
Dr. Oliver Schilling
Institute for Molecular Medicine and Cell Research,
University of Freiburg
Stefan-Meier-Str. 17
D-79104 Freiburg, Germany
Tel: +49 761 203 9615
oliver.schilling@mol-med.uni-freiburg.de read more

Post-doctoral fellowship in the biology of ADAMTS proteases and extracellular matrix.
Post-doctoral positions are available to study functions of members of the ADAMTS superfamily (ADAMTS proteases and ADAMTS-like glycoproteins) in development and disease in the lab of Suneel Apte, Cleveland USA. Candidates who wish to start in 2009 or 2010 are invited to apply. The studies encompass a variety of mouse developmental phenotypes related to extracellular matrix turnover and cell regulation, as well as human genetic disorders, cancer and arthritis. Developmental projects are relevant to early embryology, as well as the musculoskeletal and cardiovascular systems. The laboratory uses mouse and human genetics, cell biology and biochemical methods, and is suited to recently graduated PhDs or MDs, or those with expected graduation by mid-2010. The Lerner Research Institute (http://www.lerner.ccf.org) is a multidisciplinary academic institution with outstanding core facilities within a renowned medical center, The Cleveland Clinic. The Cleveland area offers a sophisticated quality of life with a relatively low cost-of-living, and a variety of outstanding recreational and cultural resources. Please send a CV, a statement of career goals and research interests, and the names and complete contact information of three references by email to: aptes@ccf.org.

POST-DOCTORAL FELLOW- University of Pennsylvania
A Postdoctoral position is available in the laboratory of Dr. Doron Greenbaum in the Department of Pharmacology, University of Pennsylvania School of Medicine to study malarial proteases in a collaborative project with an industrial partner. Our research focuses on studying protease function in the malaria parasite, P.falciparum, using a range of techniques including: (1) Functional characterization of malarial proteases using chemical, biochemical and genetic tools (2) Development of small molecule Activity-Based Probes for genome-wide protease discovery and characterization (3) Protease substrate discovery through the application of proteomics techniques to uncover proteolytic pathways (4) Recombinant expression, characterization of protease specificity and inhibitor assay development. Candidates must have a Ph.D. and/or M.D., or equivalent degree. Qualifications for the position include strong background in molecular biology and biochemistry, and a record of peer-reviewed publications. Interested individuals should e-mail a letter of intent, CV and names of three potential referees to dorong@upenn.edu.

POST-DOCTORAL FELLOW - UMC Utrecht
Applications are invited for a Postdoctoral position to work on a project investigating the role of Notch cleavage in cancer in the group of Dr. Marc Vooijs in the Department of Pathology. The successful candidate will work as a team in a multidisciplinary approach to isolate, characterize and target proteases involved in regulating Notch receptor cleavage in vivo using genomic, chemical and proteomic approaches and to validate these in mouse models for cancer. This work is funded by the ERC. We are looking for highly motivated individuals with good social skills, a solid background in molecular biology and a strong interest in translating basic research biology into clinical application for diagnosis or treatment in patients. Postdoctoral or PhD applicants with medicinal chemistry background and interest are encouraged to apply. We offer an excellent research environment in a leading academic university in Europe in an internationally oriented group performing basic and applied oncology with strong international collaborations. Applications (CV, letter of motivation and three references) should be sent as a single pdf by email to: Marc Vooijs (m.vooijs@umcutrecht.nl)