Below are our current protease-related job listings:

POSTDOCTORAL POSITION AVAILABLE IMMEDIATELY
University of Maryland - School of Medicine

Independent, motivated, early-stage postdoctoral fellows with experience in enzyme purification and an interest in secreted proteins and peptides are sought for a position in an established neurobiology/endocrinology laboratory at the University of Maryland School of Medicine in Baltimore. The successful candidate will purify two overexpressed prohormone convertases for crystallography, in one case using procedures already known to be successful in generating small crystals. He/she will also work on the regulation of prohormone convertases by endogenous mechanisms (oligomerization, the role of the inhibitory tail domain, and cellular targeting), and/or characterize novel synthetic inhibitors developed by our collaborators.

Please email a CV, a brief statement of your research interests, and the email addresses and phone numbers of three references, to Dr. Iris Lindberg at ilind001@umaryland.edu. At least one first-author paper in a refereed, English-language, journal is required for consideration.

posted 2012-12-03

POSTDOCTORAL ASSOCIATE - Immediate Opening
Wayne State University - School of Medicine

Important Note: Funding for this position is provided by the Wayne State University Vice President for Research under the Faculty Competition for Post-Doctoral Fellows. As a result of the terms of award, eligibility is limited to US citizens/permanent residents who are not and have not previously been trainees or employees at Wayne State University.

The Departments of Pharmacology and Surgery at Wayne State University are seeking to fill the position of postdoctoral associate. This is a full time position with university employee benefits. The two departments have strong collaborative ties to the Karmanos Cancer Institute and the Institute for Environmental Health Sciences and provide weekly seminars and mentoring opportunities for professional development.

Essential duties include:
* Developing 3D/4D co-culture models using microfluidic platforms and fluorescent labeling to study paracrine interactions between breast cancer cells and microvasculature
* In vitro co-cultures for drug screening and analysis by live-cell confocal imaging, cytokine immunoarrays and next gen sequencing.
* Reporting to senior scientists and clinician-scientists in the WSU School of Medicine and the Barbara Ann Karmanos Cancer Institute

The successful candidate must have the following qualifications:
* A recent PhD (awarded within the last four years) in cancer biology or related discipline
* At least two first author peer-reviewed publications
* Must be self-motivated, work well with a team, and have critical thinking abilities and a strong desire to be successful

Preferred qualifications include experience in 3D culture techniques, cytokine analysis, confocal microscopy, immunostaining, gene expression techniques including use of shRNAs and lentiviral vectors, familiarity with imaging and bioinformatics software programs.

Applications, including cv and names of three references, accepted through the Wayne State University on-line hiring system at https://jobs.wayne.edu/applicants/jsp/shared/Welcome_css.jsp. Apply posting # 038673.

Wayne State University is an Affirmative Action/Equal Employment Opportunity employer, which complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. Wayne State University is committed to a policy of nondiscrimination and equal opportunity for all persons regardless of race, sex, color, religion, national origin, age, disability or veteran status, or any other characteristic protected by applicable law.

posted 2012-12-02

POST-DOCTORAL FELLOWSHIP - Boston Biomedical Research Institute (BBRI), Watertown, MA, USA
Postdoctoral Fellow position in Functional Proteomics

A postdoctoral position immediately available for candidates with Ph.D., M.D./Ph.D., or equivalent degrees in life science disciplines, who seek superior biomedical research training. Studies will focus on characterizing proteolytic enzymes and their peptide products in complex biological samples using functional and activity-based mass spectrometry approaches.

The Boston Biomedical Research Institute (www.bbri.org) is a dynamic, independent, non-profit research institute located within minutes of all of the Boston area’s major universities and medical centers. BBRI provides a unique training environment focused expressly on the career development of post-doctoral associates and supported by state-of-the-art equipment and facilities. Competitive compensation and benefit packages are available, including retirement benefits for appointees who meet the eligibility requirements.

To apply, send statement of research interests and career goals, curriculum vitae and contact information for three references to Markus Hardt, Ph.D. (hardt@bbri.org).

BBRI is an Equal Opportunity Employer. Hire is contingent upon eligibility to work in the United States.

posted 2012-03-08